Medividia Computer simulation for heart valves and cardiovascular devices
Heart-valve FSI visualization combining anatomical geometry and flow trajectories

Heart valve simulation from early design to regulatory evidence

Better heart valve development decisions
with Fluid-Structure Interaction simulations.

Reveal how design, deployment, anatomy, leaflet motion and blood flow influence valve performance.

We partner with simulation teams and R&D leaders to support valve design, preclinical evaluation and regulatory evidence generation using coupled Abaqus and FlowVision FSI.

Explore FlowVision CFD software
FSI & CFD Software Deploy FlowVision Build robust Fluid-Structure Interaction workflows by coupling FlowVision with Abaqus structural simulation. Visit FlowVisionCFD.com

With Medividia from ideation to market

From early design to simulation evidence that complements clinical data
and supports regulatory submissions.

Start with a focused design comparison, add FSI to your existing simulation capabilities, or integrate a complete evaluation pipeline with validation and traceability into your device program.

Medividia development workflow linking early design and design iteration with virtual bench testing, physical prototyping, animal validation, in-silico human models and patient-specific studies through clinical development.
View full-size workflow

Design Screening
and Virtual Bench Testing

Screen design concepts, compare performance tradeoffs and evaluate selected candidates under physiological or standardized virtual bench conditions before committing to physical prototypes and testing.

Virtual bench evaluationLeaflet motion and downstream flow views.

Patient-Specific Simulation

Evaluate device performance in patient anatomies reconstructed from clinical data or in systematically generated virtual patients, including variations in sizing, deployment and physiology.

Patient-specific right-heart simulation showing intracardiac flow streamlines and an implanted valve.
Patient-specific right-heart FSI

Clinical and Regulatory Support

Complement bench and clinical data, investigate observed outcomes and generate traceable simulation evidence addressing device performance and variability for regulatory submissions.

Multiple patient-specific anatomies and implanted valve configurations shown from side and en-face views.
Selected patient-specific valve configurations
Finite element analysis CFD FSI Virtual bench Patient-specific simulation In silico trials

How FSI accelerates development

Discover risks while the design can still change.
Support clinical and regulatory programs with simulation evidence.

FSI can reveal design weaknesses and identify the design or deployment variables behind them. Engineers can apply a targeted correction and test its effect virtually before producing the next prototype. The improved design can then advance to patient-specific simulation under realistic clinical conditions and ultimately contribute to regulatory evidence.

  1. 01Discover potential failure modes before physical testing
  2. 02Identify the underlying failure mechanism
  3. 03Test a targeted correction before the next prototype
  4. 04Evaluate performance under virtual in vivo conditions
  5. 05Support clinical and regulatory programs with simulation evidence

Deployment Decisions

Which deployment is better?

Compare how deployment position changes leaflet opening and closure. Use the coupled response to investigate the tradeoffs before selecting the next configuration to test.

Annular and supra-annular deploymentSelected leaflet configurations at two phases of the cycle.

Device and Anatomy

How does the device fit this anatomy?

Bring the frame, leaflets, surrounding tissue and calcification into the same model to investigate the deployed configuration.

Device and anatomy in one modelValve frame, leaflets and surrounding anatomical structures.

Applications: Heart Valves and Beyond

Validated heart valve workflows and specialized simulation technology
for blood-contacting devices.

Our team has been modeling and simulating heart valves since 2008, supporting global manufacturers and developing tailored simulation software for blood damage and thrombogenicity assessment. This expertise extends to blood pumps, including LVADs and RVADs, PFO, ASD and LAA occluders, filters and other blood-contacting devices.

Heart Valve FSI

Device + Blood + Anatomy.One system, as in real life.

Assess leaflet kinematics, coaptation and stress together with the coupled hemodynamic response, including pressure gradients, regurgitation and washout, under realistic virtual bench and in vivo conditions.

Explore FSI simulations of heart valves
TAVR simulation in the Living Heart Human Model: leaflet motion and time-varying blood-flow velocity.

Beyond Heart Valves

Reveal the flow mechanisms shaping the performance and safety of blood-contacting devices.

Use advanced FSI and multiphysics CFD to evaluate device performance, flow fields, shear exposure, and indicators of blood damage and thrombogenicity.

Explore cardiovascular applications

How We Work

Engage us for a pilot, a full-scale program
or an investment in future simulation capability.

Partner with a highly specialized simulation team that adapts to your organization, at any phase of development and any level of complexity. Work with us for hands-on simulation delivery, software integration or tailored technology development.

Trustworthiness: Verification & Validation

Credibility built on structured verification and validation
for the intended context of use.

Explore how our software is verified, numerical accuracy is checked in each simulation campaign, simulations are compared with physical measurements, and uncertainties are assessed for their impact on results and decisions. Confidence in our software and workflows comes from transparent, well-documented processes.

Validated Valve Performance and More

Blind validation studies compare predicted TPG, EOA and RF with measurements across multiple valves and operating conditions. Selected studies also examine leaflet contact, flow fields and kinematics.

Request our valve validation data

Robust and Reliable Toolset

We combine Abaqus structural simulation with FlowVision fluid dynamics in a robust FSI workflow for capturing the coupled behavior of valves and other blood-contacting devices.

Request our FDA benchmark comparisons

Aerospace-Inspired Quality Control

Structured checklists, documented formulations and systematic cross-checks bring aerospace-inspired discipline to simulation delivery, helping reduce the risk of human error in manual operations.

Start a Conversation

Let’s explore how we can work together.

Tell us about your device program, engineering questions or the simulation capability you want to build. We’ll help identify a practical next step.

Book a meeting Send an inquiry